Software solutions for the livestock genomics SNP array revolution
نویسندگان
چکیده
منابع مشابه
SNPConvert: SNP Array Standardization and Integration in Livestock Species
One of the main advantages of single nucleotide polymorphism (SNP) array technology is providing genotype calls for a specific number of SNP markers at a relatively low cost. Since its first application in animal genetics, the number of available SNP arrays for each species has been constantly increasing. However, conversely to that observed in whole genome sequence data analysis, SNP array dat...
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John Sulston, who coordinated the UK side of the international publicly funded efforts to sequence ‘the’ human genome, once said the endeavour was like a moon shot. He may only have referred to the scale and ambition of the project, but one could argue that, in both cases, outdated technology and extraordinary amounts of money were used to hit a highly visible and prestigious target, just to sh...
متن کاملLandscape Genomics in Livestock
Landscape genomics correlates genetic variation patterns with geographic variables to investigate how geographical and environmental characteristics affect the genetic structure of populations (Luikart et al., 2003; Joost et al., 2007; Holderegger & Wagner, 2008; Pariset et al., 2009; Shwartz et al., 2009). A field combining molecular markers, genetics and landscape structure was first describe...
متن کاملEvaluating the influence of quality control decisions and software algorithms on SNP calling for the affymetrix 6.0 SNP array platform.
OBJECTIVE Our goal was to evaluate the influence of quality control (QC) decisions using two genotype calling algorithms, CRLMM and Birdseed, designed for the Affymetrix SNP Array 6.0. METHODS Various QC options were tried using the two algorithms and comparisons were made on subject and call rate and on association results using two data sets. RESULTS For Birdseed, we recommend using the c...
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ژورنال
عنوان ژورنال: Animal Genetics
سال: 2015
ISSN: 0268-9146
DOI: 10.1111/age.12295